| Definition of 'angiotensin-converting enzyme inhibitors' |
U.S. National Library of Medicine |
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1. angiotensin-converting enzyme inhibitors
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
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