Definitions for amyotrophic lateral sclerosis
ˌeɪ maɪ əˈtrɒf ɪk, -ˈtroʊ fɪk, eɪˌmaɪ ə-amy·otroph·ic lat·er·al scle·ro·sis

Princeton's WordNetRate this definition:0.0 / 0 votes

1. amyotrophic lateral sclerosis, ALS, Lou Gehrig's diseasenoun

   thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs

WiktionaryRate this definition:0.0 / 0 votes

1. amyotrophic lateral sclerosisnoun

   A chronic, progressive disease characterized by degeneration of the central nervous system and the loss of voluntary muscle control.

WikipediaRate this definition:0.0 / 0 votes

1. amyotrophic lateral sclerosis

   Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a neurodegenerative disease that results in the progressive loss of motor neurons that control voluntary muscles. ALS is the most common form of the motor neuron diseases. Early symptoms of ALS include stiff muscles, muscle twitches, and gradual increasing weakness and muscle wasting. Limb-onset ALS begins with weakness in the arms or legs, while bulbar-onset ALS begins with difficulty speaking or swallowing. Around half of people with ALS develop at least mild difficulties with thinking and behavior, and about 15% develop frontotemporal dementia. Motor neuron loss continues until the ability to eat, speak, move, and finally the ability to breathe is lost with the cause of early death usually being respiratory failure.Most cases of ALS (about 90% to 95%) have no known cause, and are known as sporadic ALS. However, both genetic and environmental factors are believed to be involved. The remaining 5% to 10% of cases have a genetic cause linked to a history of the disease in the family, and these are known as familial ALS. About half of these genetic cases are due to one of two specific genes. The diagnosis is based on a person's signs and symptoms, with testing done to rule out other potential causes.There is no known cure for ALS. The goal of treatment is to improve symptoms. A medication called riluzole may extend life by about two to three months. Non-invasive ventilation may result in both improved quality and length of life. Mechanical ventilation can prolong survival but does not stop disease progression, with death usually caused by respiratory failure. A feeding tube may help. The disease can affect people of any age, but usually starts around the age of 60. The average survival from onset to death is two to four years, though this can vary, and about 10% survive longer than 10 yearsDescriptions of the disease date back to at least 1824 by Charles Bell. In 1869, the connection between the symptoms and the underlying neurological problems was first described by French neurologist Jean-Martin Charcot, who in 1874 began using the term amyotrophic lateral sclerosis.

ChatGPTRate this definition:0.0 / 0 votes

1. amyotrophic lateral sclerosis

   Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. This disease leads to the loss of motor neurons, cells that control muscle movements, which in turn results in muscle weakness and eventually an inability to move. ALS is characterized by stiff muscles, muscle twitching, and worsening weakness due to decreased muscle size. It can also affect speech, swallowing, and breathing, reducing the patient’s quality of life. It's a rare disease with no known cure as of now.

WikidataRate this definition:0.0 / 0 votes

1. Amyotrophic lateral sclerosis

   Amyotrophic lateral sclerosis – also referred to as motor neurone disease in some Commonwealth of Nations countries and as Lou Gehrig's disease in the United States – is a debilitating disease with varied etiology characterized by rapidly progressive weakness, muscle atrophy and fasciculations, muscle spasticity, difficulty speaking, difficulty swallowing, and difficulty breathing. ALS is the most common of the five motor neuron diseases.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Amyotrophic Lateral Sclerosis

   A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)

Matched Categories

1. • Nervous Disorder
   • Sclerosis

How to pronounce amyotrophic lateral sclerosis?

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Numerology

1. Chaldean Numerology

   The numerical value of amyotrophic lateral sclerosis in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of amyotrophic lateral sclerosis in Pythagorean Numerology is: 7

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=amyotrophic lateral sclerosis
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Amyotrophic_Lateral_Sclerosis
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Amyotrophic_Lateral_Sclerosis
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=amyotrophic lateral sclerosis