Definitions for alpidem
alpi·dem

WiktionaryRate this definition:0.0 / 0 votes

1. alpidemnoun

   An anxiolytic imidazopyridine drug that is related to zolpidem.

WikipediaRate this definition:0.0 / 0 votes

1. Alpidem

   Alpidem, sold under the brand name Ananxyl, is a nonbenzodiazepine anxiolytic medication which was briefly used to treat anxiety disorders but is no longer marketed. It was previously marketed in France, but was discontinued due to liver toxicity. Alpidem is taken by mouth.Side effects of alpidem include sedation, fatigue, dizziness, and headache, among others. It has much less to no impact on cognition, memory, and psychomotor function relative to benzodiazepines. Similarly, no rebound anxiety or withdrawal symptoms have been observed with alpidem. Rarely, alpidem can cause serious liver toxicity, including liver failure and death. Alpidem is a nonbenzodiazepine of the imidazopyridine family, structurally related to the Z-drug zolpidem, and acts as a GABAA receptor positive allosteric modulator of the benzodiazepine site of the receptor complex. In contrast to zolpidem however, alpidem has anxiolytic effects rather than sedative or hypnotic effects at normal therapeutic doses.Alpidem was first described by 1982 and was introduced for medical use in France in 1991. It was also under development for use in other countries in the 1990s, but development was discontinued and the drug was never marketed in any other country. Alpidem was withdrawn from the market in France in 1993 due to liver toxicity.

WikidataRate this definition:0.0 / 0 votes

1. Alpidem

   Alpidem is an anxiolytic drug from the imidazopyridine family, related to the more well known sleeping medication zolpidem. Unlike zolpidem however, alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety. Alipidem was developed by Synthélabo. It was approved for marketing in France in 1991. Clinical trial to obtain US FDA approval were halted in 1992 and the drug never received FDA approval. It was withdrawn from the French market by 1994 and is not approved for marketing anywhere in the world. Alpidem was known to act selectively on the α3 receptor subtype and to a lesser extent at the α1 subtype, of the benzodiazepine receptor. However the chemical structure of alpidem is not related to that of the benzodiazepines, and alpidem is thus sometimes referred to as a nonbenzodiazepine.

Anagrams for alpidem »

1. impaled

2. implead

How to pronounce alpidem?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say alpidem in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of alpidem in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of alpidem in Pythagorean Numerology is: 6

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Alpidem
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Alpidem
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=alpidem