Definitions for alfacalcidol

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  1. Alfacalcidol

    Alfacalcidol is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive. Alfacalcidol has a weaker impact on calcium metabolism than calcitriol, while having more potent effects on parathyroid hormone levels and the immune system, including regulatory T cells. It is considered to be a more useful form of vitamin D supplementation, mostly due to much longer half-life and lower kidney load. Used as a poultry feed additive, it prevents tibial dyschondroplasia and increases phytate bioavailability.

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