Definitions for aldosterone
ˌæl doʊ stɪˈroʊn, ˈæl doʊ stɪˌroʊn, ælˈdɒs təˌroʊnal·dos·terone

Princeton's WordNetRate this definition:0.0 / 0 votes

1. aldosteronenoun

   a corticosteroid hormone that is secreted by the cortex of the adrenal gland; regulates salt (sodium and potassium) and water balance

WiktionaryRate this definition:0.0 / 0 votes

1. aldosteronenoun

   A mineralocorticoid hormone, secreted by the adrenal cortex, that regulates the balance of sodium and potassium in the body.

WikipediaRate this definition:0.0 / 0 votes

1. Aldosterone

   Aldosterone is the main mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. It is essential for sodium conservation in the kidney, salivary glands, sweat glands, and colon. It plays a central role in the homeostatic regulation of blood pressure, plasma sodium (Na+), and potassium (K+) levels. It does so primarily by acting on the mineralocorticoid receptors in the distal tubules and collecting ducts of the nephron. It influences the reabsorption of sodium and excretion of potassium (from and into the tubular fluids, respectively) of the kidney, thereby indirectly influencing water retention or loss, blood pressure, and blood volume. When dysregulated, aldosterone is pathogenic and contributes to the development and progression of cardiovascular and kidney disease. Aldosterone has exactly the opposite function of the atrial natriuretic hormone secreted by the heart.Aldosterone is part of the renin–angiotensin–aldosterone system. It has a plasma half-life of less than 20 minutes. Drugs that interfere with the secretion or action of aldosterone are in use as antihypertensives, like lisinopril, which lowers blood pressure by blocking the angiotensin-converting enzyme (ACE), leading to lower aldosterone secretion. The net effect of these drugs is to reduce sodium and water retention but increase retention of potassium. In other words, these drugs stimulate the excretion of sodium and water in urine, while they block the excretion of potassium. Another example is spironolactone, a potassium-sparing diuretic of the steroidal spirolactone group, which interferes with the aldosterone receptor (among others) leading to lower blood pressure by the mechanism described above. Aldosterone was first isolated by Sylvia Tait (Simpson) and Jim Tait in 1953; in collaboration with Tadeusz Reichstein.

ChatGPTRate this definition:0.0 / 0 votes

1. aldosterone

   Aldosterone is a steroid hormone produced by the adrenal glands that plays a crucial role in the regulation of blood pressure. It does this by balancing the concentration of sodium and potassium in the bloodstream, which in turn helps control the amount of fluid in the body and thus blood pressure levels. Aldosterone can increase sodium reabsorption and potassium excretion, and it also stimulates the secretion of hydrogen ions into the lumen of the kidney. Its production and release are regulated by the renin-angiotensin-aldosterone system.

WikidataRate this definition:0.0 / 0 votes

1. Aldosterone

   Aldosterone is a steroid hormone produced by the outer section of the adrenal cortex in the adrenal gland. It plays a central role in the regulation of blood pressure mainly by acting on the distal tubules and collecting ducts of the nephron, increasing reabsorption of ions and water in the kidney, to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. When dysregulated, aldosterone is pathogenic and contributes to the development and progression of cardiovascular and renal disease. Although sustained production of aldosterone requires persistent calcium entry through low-voltage activated Ca2+ channels, isolated zona glomerulosa cells are considered nonexcitable, with recorded membrane voltages that are too hyperpolarized to permit Ca2+ channels entry. However, mouse zona glomerulosa cells within adrenal slices spontaneously generate membrane potential oscillations of low periodicity; this innate electrical excitability of zona glomerulosa cells provides a platform for the production of a recurrent Ca2+ channels signal that can be controlled by angiotensin II and extracellular potassium, the 2 major regulators of aldosterone production. Aldosterone has exactly the opposite function of the atrial natriuretic hormone secreted by the heart.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Aldosterone

   A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

Editors ContributionRate this definition:0.0 / 0 votes

1. aldosterone

   Is a type of hormone produced naturally in the body of a human being.

   Aldosterone regulates specific elements in the body.

   
   

   Submitted by MaryC on June 8, 2020  

Matched Categories

1. • Mineralocorticoid

How to pronounce aldosterone?

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Numerology

1. Chaldean Numerology

   The numerical value of aldosterone in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of aldosterone in Pythagorean Numerology is: 2

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=aldosterone
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Aldosterone
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Aldosterone
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=aldosterone