Definitions for aids dementia complex
aids de·men·tia com·plex

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1. AIDS dementia complex

   AIDS dementia complex is a common neurological disorder associated with HIV infection and AIDS. It is a metabolic encephalopathy induced by HIV infection and fueled by immune activation of macrophages and microglia. These cells are actively infected with HIV and secrete neurotoxins of both host and viral origin. The essential features of ADC are disabling cognitive impairment accompanied by motor dysfunction, speech problems and behavioral change. Cognitive impairment is characterised by mental slowness, trouble with memory and poor concentration. Motor symptoms include a loss of fine motor control leading to clumsiness, poor balance and tremors. Behavioral changes may include apathy, lethargy and diminished emotional responses and spontaneity. Histopathologically, it is identified by the infiltration of monocytes and macrophages into the central nervous system, gliosis, pallor of myelin sheaths, abnormalities of dendritic processes and neuronal loss. ADC typically occurs after years of HIV infection and is associated with low CD4+ T cell levels and high plasma viral loads. It is sometimes seen as the first sign of the onset of AIDS. Prevalence is between 10-24% in Western countries and has only been seen in 1-2% of India based infections. With the advent of highly active antiretroviral therapy, the incidence of ADC has declined in developed countries, although its prevalence is increasing. HAART may prevent or delay the onset of ADC in people with HIV infection, and may also improve mental function in people who already have ADC.

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1. AIDS Dementia Complex

   A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

How to pronounce aids dementia complex?

1. Alex

   US English

   David

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   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

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   Fred

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   Tessa

   South African

How to say aids dementia complex in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of aids dementia complex in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of aids dementia complex in Pythagorean Numerology is: 3

References

1. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=aids dementia complex