The amine (4-aminobutyl)guanidine which is a decarboxylation product of arginine and an intermediate in polyamine biosynthesis
Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is discussed as a putative neurotransmitter. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase. Agmatine binds to α2-adrenergic receptor and imidazoline binding sites, and blocks NMDA receptors and other cation ligand-gated channels. Agmatine inhibits nitric oxide synthase, and it induces the release of some peptide hormones.
U.S. National Library of Medicine
Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.
The numerical value of agmatine in Chaldean Numerology is: 6
The numerical value of agmatine in Pythagorean Numerology is: 7
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