1. adhesins, bacterial Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteriafunction as adhesins, but in many cases it is a minorsubunitprotein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharidesurfacelayer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.