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 Definitions of acquired hyperostosis syndrome  

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Definition of 'acquired hyperostosis syndrome' U.S. National Library of Medicine 

1.  acquired hyperostosis syndrome
Syndrome consisting of synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis (SAPHO). The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.



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