Definitions for acantholysis
This page provides all possible meanings and translations of the word acantholysis
a breakdown of a cell layer in the epidermis (as in pemphigus)
The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris.
Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris. It is absent in bullous pemphigoid, making it useful for differential diagnosis. This histological feature is also seen in herpes simplex infections.
U.S. National Library of Medicine
Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE.
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