Definitions for ZidoVuDine
zaɪˈdoʊ vyuˌdinzi·dovu·dine

Princeton's WordNetRate this definition:0.0 / 0 votes

1. zidovudine, Retrovir, ZDV, AZTnoun

   an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow

WiktionaryRate this definition:0.0 / 0 votes

1. zidovudinenoun

   A nucleoside analog reverse transcriptase inhibitor, a type of antiretroviral drug, the first approved treatment for HIV.

WikipediaRate this definition:0.0 / 0 votes

1. Zidovudine

   Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. It may be used to prevent mother-to-child spread during birth or after a needlestick injury or other potential exposure. It is sold both by itself and together as lamivudine/zidovudine and abacavir/lamivudine/zidovudine. It can be used by mouth or by slow injection into a vein.Common side effects include headaches, fever, and nausea. Serious side effects include liver problems, muscle damage, and high blood lactate levels. It is commonly used in pregnancy and appears to be safe for the baby. ZDV is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. It works by inhibiting the enzyme reverse transcriptase that HIV uses to make DNA and therefore decreases replication of the virus.Zidovudine was first described in 1964. It was approved in the United States in 1987 and was the first treatment for HIV. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.

ChatGPTRate this definition:0.0 / 0 votes

1. zidovudine

   Zidovudine, also known as AZT, is an antiretroviral medication used to prevent and treat HIV/AIDS. It slows down the progression of the disease by inhibiting the replication of the virus in the body. Zidovudine is often used in combination with other antiretroviral drugs in what is known as antiretroviral therapy (ART). It can also be used to prevent mother-to-child transmission of HIV during childbirth or after a needlestick injury or other potential exposure.

WikidataRate this definition:0.0 / 0 votes

1. Zidovudine

   Zidovudine or azidothymidine is a nucleoside analog reverse-transcriptase inhibitor, a type of antiretroviral drug used for the treatment of HIV/AIDS infection. AZT is the first U.S. government-approved treatment for HIV therapy, prescribed under the name Retrovir. AZT was the first breakthrough in AIDS therapy, significantly reducing the replication of the virus in patients and leading to clinical and immunologic improvements. It can also be used to prevent HIV transmission, such as from mother to child during the period of birth or after a needle stick. Used by itself in HIV-infected patients, AZT safely slows HIV replication in patients, but generally does not stop it entirely. This may allow HIV to become AZT-resistant over time, and for this reason AZT is usually used in conjunction with the other anti-HIV drugs in combination therapy called highly active antiretroviral therapy. To simplify its use in combination, AZT is included in Combivir and Trizivir, among others. Zidovudine is included in the World Health Organization's Model List of Essential Medicines, which suggests the minimum medicinal needs for a basic health care system.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Zidovudine

   A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.

Matched Categories

1. • Nucleoside Reverse Transcriptase Inhibitor

How to pronounce ZidoVuDine?

1. Alex

   US English

   David

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   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

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   Fred

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   Tessa

   South African

How to say ZidoVuDine in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of ZidoVuDine in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of ZidoVuDine in Pythagorean Numerology is: 3

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=ZidoVuDine
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Zidovudine
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Zidovudine
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=ZidoVuDine