What does SPEN mean?

Definitions for SPEN
spen

This dictionary definitions page includes all the possible meanings, example usage and translations of the word SPEN.


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Wikipedia

  1. SPEN

    Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.

Wikidata

  1. SPEN

    Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene. This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.

Suggested Resources

  1. SPEN

    What does SPEN stand for? -- Explore the various meanings for the SPEN acronym on the Abbreviations.com website.

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Numerology

  1. Chaldean Numerology

    The numerical value of SPEN in Chaldean Numerology is: 3

  2. Pythagorean Numerology

    The numerical value of SPEN in Pythagorean Numerology is: 9

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"SPEN." Definitions.net. STANDS4 LLC, 2024. Web. 18 Apr. 2024. <https://www.definitions.net/definition/SPEN>.

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