PANDAS is an acronym for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections, a rare disease that usually appears in children. This term describes a hypothesis that there exists a subset of children with rapid onset of obsessive-compulsive disorder and/or tic disorders and these symptoms are caused by group A beta-hemolytic streptococcal infections. The proposed link between infection and these disorders is that an initial autoimmune reaction to a GABHS infection produces antibodies that continues to interfere with basal ganglia function, causing symptom exacerbations. The PANDAS hypothesis was based on observations in clinical case studies at the US National Institute of Health and in subsequent clinical trials where children appeared to have dramatic and sudden OCD exacerbations and tic disorders following infections. There is supportive evidence for the link between streptococcus infection and onset in some cases of OCD and tics, but proof of causality has remained elusive. The PANDAS hypothesis is controversial; whether it is a distinct entity differing from other cases of Tourette syndrome /OCD is debated.
The numerical value of PANDAS in Chaldean Numerology is: 4
The numerical value of PANDAS in Pythagorean Numerology is: 1
Sample Sentences & Example Usage
The rise in the population of wild giant pandas is a victory for conservation and definitely one to celebrate.
It is rare for pandas to live to this age, it's probably equivalent to someone, a human person, who would be over a hundred years of age.
China's national treasure pandas coming to South Korea is a good example to show bilateral cooperation for the protection of the environment.
Capital gains and the expectations for future gains will become Giant Pandas – very rare and sort of inefficient at reproduction, i'm saying that developed and emerging economies are flying at stall speed and they've got to bump up nominal GDP growth rates or else. Cross your fingers.
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