What does Major Histocompatibility Complex mean?
Definitions for Major Histocompatibility Complex
ma·jor his·to·com·pat·i·bil·i·ty com·plex
This dictionary definitions page includes all the possible meanings, example usage and translations of the word Major Histocompatibility Complex.
Wikidata
Major histocompatibility complex
The major histocompatibility complex is a cell surface molecule encoded by a large gene family in all vertebrates. MHC molecules mediate interactions of leukocytes, also called white blood cells, which are immune cells, with other leukocytes or body cells. MHC determines compatibility of donors for organ transplant as well as one's susceptibility to an autoimmune disease via crossreacting immunization. In humans, MHC is also called human leukocyte antigen. Protein molecules—either of the host's own phenotype or of other biologic entities—are continually synthesized and degraded in a cell. Occurring on the cell surface, each MHC molecule displays a molecular fraction, called epitope, of a protein. The presented antigen can be either self or nonself. On the cell membrane, the MHC population in its entirety is like a meter indicating the balance of proteins within the cell. The MHC gene family is divided into three subgroups: class I, class II and class III. Diversity of antigen presentation, mediated by MHC classes I and II, is attained in multiple ways: the MHC's genetic encoding is polygenic, MHC genes are highly polymorphic and have many variants, several MHC genes are expressed from both inherited alleles.
U.S. National Library of Medicine
Major Histocompatibility Complex
The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD) TRANSPLANTATION ANTIGENS, genes which control the structure of the IMMUNE RESPONSE-ASSOCIATED ANTIGENS, HUMAN; the IMMUNE RESPONSE GENES which control the ability of an animal to respond immunologically to antigenic stimuli, and genes which determine the structure and/or level of the first four components of complement.
Numerology
Chaldean Numerology
The numerical value of Major Histocompatibility Complex in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of Major Histocompatibility Complex in Pythagorean Numerology is: 1
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"Major Histocompatibility Complex." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/Major+Histocompatibility+Complex>.
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