What does Lethal Dose mean?

Definitions for Lethal Dose
lethal dose

This dictionary definitions page includes all the possible meanings, example usage and translations of the word Lethal Dose.

Princeton's WordNet

  1. lethal dosenoun

    the size dose that will cause death

Wiktionary

  1. lethal dosenoun

    the dose of a substance or of radiation likely to cause death (sometimes suffixed with a number)

ChatGPT

  1. lethal dose

    A lethal dose refers to the specific amount of a substance or form of radiation that is sufficient to kill an organism, typically humans. It is usually expressed as LD50, meaning the dose that would be fatal to 50% of the population it is tested on. This measure is commonly used in toxicology to determine the relative safety or danger of a substance.

Wikidata

  1. Lethal dose

    A lethal dose is an indication of the lethality of a given substance or type of radiation. Because resistance varies from one individual to another, the 'lethal dose' represents a dose at which a given percentage of subjects will die. The LD may be based on the standard person concept, a theoretical individual that has perfectly "normal" characteristics, and thus not apply to all sub-populations. Lethal doses are usually expressed as median lethal dose, the point where 50% of test subjects exposed would die, in the units of mg/kg body weight. For gases and aerosols, lethal concentration is the analogous concept, although this also depends on the duration of exposure, which has to be included in the definition. The lowest known lethal dose, derived from an individual case of poisoning, is abbreviated LCLo. LD values for humans are best estimated by extrapolating results from human cell cultures. One outdated form of extrapolation involves measuring LD on animals like mice or dogs, converting to dosage per kilogram of biomass, and extrapolating to human norms. The degree of error from animal-extrapolated LD values is very large. The biology of test animals differs in important aspects to that of humans. For instance, mouse tissue is approximately fifty times less responsive than human tissue to the venom of the Sydney funnel-web spider. The square-cube law also complicates the scaling relationships involved. Researchers are now shifting away from animal-based LD measurements. The U.S. Food and Drug Administration has begun to approve more reliable non-animal methods in response to research cruelty concerns and the lack of validity/sensitivity of animal tests as they relate to humans.

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Numerology

  1. Chaldean Numerology

    The numerical value of Lethal Dose in Chaldean Numerology is: 4

  2. Pythagorean Numerology

    The numerical value of Lethal Dose in Pythagorean Numerology is: 2

Examples of Lethal Dose in a Sentence

  1. Rahul Gupta:

    It is an evolving process because now we're seeing these pills, counterfeit drugs that are often being marketed through social media to impact youth, and the fact is…if you're attempting to obtain drugs anywhere other than prescription drugs through a legitimate pharmacy, two out of five chances are there that they will have fentanyl, often a lethal dose in it.

  2. Donna Iula:

    If you think carfentanil is scary, there are actually compounds in the literature that are more potent, a lethal dose is not even visible to the eye.

  3. Andrew Timmins:

    Not all animals that eat chocolate will automatically die, but it is clearly evident that wild animals can consume enough chocolate to reach a lethal dose.

  4. Akiko Iwasaki:

    That approach we have shown in the mouse model to be 100 % protective against lethal dose of SARS-CoV-2 infection, and it dramatically reduces the viral load in the nose and in the lung.

  5. Scott Oulton:

    Lately, we’ve been seeing a purity increase over the last year, where we used to say roughly four out of the 10 seizures that we were receiving would contain a lethal dose of greater than 2 milligrams. As of October last year, we started reporting that we’ve seen an uptick. Now we’re saying that six out of 10 of the seizures that we’re receiving contain over 2 milligrams.


Translations for Lethal Dose

From our Multilingual Translation Dictionary

  • घातक खुराकHindi
  • ಮಾರಕ ಪ್ರಮಾಣKannada

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"Lethal Dose." Definitions.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.definitions.net/definition/Lethal+Dose>.

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