Definitions for Kulinkovich reaction
This page provides all possible meanings and translations of the word Kulinkovich reaction
The organic synthesis of cyclopropanols via reaction of esters with dialkyldialkoxytitanium reagents, generated in situ from Grignard reagents bearing hydrogen in beta-position and titanium(IV) alkoxides such as titanium isopropoxide.
The Kulinkovich reaction describes the organic synthesis of cyclopropanols via reaction of esters with dialkyldialkoxytitanium reagents, generated in situ from Grignard reagents bearing hydrogen in beta-position and titanium alkoxides such as titanium isopropoxide. This reaction was discovered by Kulinkovich and coworkers in 1989. The titanium reagent can be used catalytically. Titanium catalysts are ClTi(OiPr)3 or Ti(OiPr)4, ClTi(OtBu)3 or Ti(OtBu)4, Grignard reagents are EtMgX, PrMgX or BuMgX. Solvents can be Et2O, THF, Toluol. Tolerated Functional Groups: Ethers R–O–R, R–S–R, Imines RN=CHR. Amides, primary and secondary amines, carbamates are not stable to the reaction condition An asymmetric version of this reaction is also known with a TADDOL-based catalyst.
The numerical value of Kulinkovich reaction in Chaldean Numerology is: 6
The numerical value of Kulinkovich reaction in Pythagorean Numerology is: 4
Images & Illustrations of Kulinkovich reaction
Find a translation for the Kulinkovich reaction definition in other languages:
Select another language:
Discuss these Kulinkovich reaction definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"Kulinkovich reaction." Definitions.net. STANDS4 LLC, 2017. Web. 22 Jan. 2017. <http://www.definitions.net/definition/Kulinkovich reaction>.