What does KRAS mean?
Definitions for KRAS
kras
This dictionary definitions page includes all the possible meanings, example usage and translations of the word KRAS.
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Wikipedia
KRAS
KRAS (Kirsten rat sarcoma virus) is a gene that provides instructions for making a protein called K-Ras, a part of the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell's nucleus. These signals instruct the cell to grow and divide (proliferate) or to mature and take on specialized functions (differentiate). It is called KRAS because it was first identified as a viral oncogene in the Kirsten RAt Sarcoma virus. The oncogene identified was derived from a cellular genome, so KRAS, when found in a cellular genome, is called a proto-oncogene. The K-Ras protein is a GTPase, a class of enzymes which convert the nucleotide guanosine triphosphate (GTP) into guanosine diphosphate (GDP). In this way the K-Ras protein acts like a switch that is turned on and off by the GTP and GDP molecules. To transmit signals, it must be turned on by attaching (binding) to a molecule of GTP. The K-Ras protein is turned off (inactivated) when it converts the GTP to GDP. When the protein is bound to GDP, it does not relay signals to the nucleus. The gene product of KRAS, the K-Ras protein, was first found as a p21 GTPase. Like other members of the ras subfamily of GTPases, the K-Ras protein is an early player in many signal transduction pathways. K-Ras is usually tethered to cell membranes because of the presence of an isoprene group on its C-terminus. There are two protein products of the KRAS gene in mammalian cells that result from the use of alternative exon 4 (exon 4A and 4B respectively): K-Ras4A and K-Ras4B. These proteins have different structures in their C-terminal region and use different mechanisms to localize to cellular membranes, including the plasma membrane.
Wikidata
Kras
Karst, also known as the Karst Plateau, is a limestone borderline plateau region extending in southwestern Slovenia and northeastern Italy. It lies between the Vipava Valley, the low hills surrounding the valley, the westernmost part of the Brkini Hills, northern Istria, and the Gulf of Trieste. The western edge of the plateau also marks the traditional ethnic border between Italians and Slovenes. The region gave its name to the karst topography. For this reason, it is also referred to as the Classical Karst.
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KRAS
What does KRAS stand for? -- Explore the various meanings for the KRAS acronym on the Abbreviations.com website.
Surnames Frequency by Census Records
KRAS
According to the U.S. Census Bureau, Kras is ranked #47429 in terms of the most common surnames in America.
The Kras surname appeared 447 times in the 2010 census and if you were to sample 100,000 people in the United States, approximately 0 would have the surname Kras.
94.4% or 422 total occurrences were White.
2.2% or 10 total occurrences were of two or more races.
2.2% or 10 total occurrences were of Hispanic origin.
Anagrams for KRAS »
askr
sark
Numerology
Chaldean Numerology
The numerical value of KRAS in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of KRAS in Pythagorean Numerology is: 4
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Translations for KRAS
From our Multilingual Translation Dictionary
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