Definitions for G protein
g protein

WiktionaryRate this definition:0.0 / 0 votes

1. G proteinnoun

   Any of a class of proteins, found in cell membranes, that pass signals between hormone receptors and effector enzymes

2. Etymology: *guanine nucleotide binding protein

WikipediaRate this definition:0.0 / 0 votes

1. G protein

   G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior. Their activity is regulated by factors that control their ability to bind to and hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP). When they are bound to GTP, they are 'on', and, when they are bound to GDP, they are 'off'. G proteins belong to the larger group of enzymes called GTPases. There are two classes of G proteins. The first function as monomeric small GTPases (small G-proteins), while the second function as heterotrimeric G protein complexes. The latter class of complexes is made up of alpha (α), beta (β) and gamma (γ) subunits. In addition, the beta and gamma subunits can form a stable dimeric complex referred to as the beta-gamma complex .Heterotrimeric G proteins located within the cell are activated by G protein-coupled receptors (GPCRs) that span the cell membrane. Signaling molecules bind to a domain of the GPCR located outside the cell, and an intracellular GPCR domain then in turn activates a particular G protein. Some active-state GPCRs have also been shown to be "pre-coupled" with G proteins, whereas in other cases a collision coupling mechanism is thought to occur. The G protein activates a cascade of further signaling events that finally results in a change in cell function. G protein-coupled receptor and G proteins working together transmit signals from many hormones, neurotransmitters, and other signaling factors. G proteins regulate metabolic enzymes, ion channels, transporter proteins, and other parts of the cell machinery, controlling transcription, motility, contractility, and secretion, which in turn regulate diverse systemic functions such as embryonic development, learning and memory, and homeostasis.

WikidataRate this definition:0.0 / 0 votes

1. G protein

   G proteins, also known as guanosine nucleotide-binding proteins, are a family of proteins involved in transmitting signals from a variety of different stimuli outside a cell into the inside of the cell. G proteins function as molecular switches. Their activity is regulated by factors that control their ability to bind to and hydrolyze guanosine triphosphate to guanosine diphosphate. When they bind GTP, they are 'on', and, when they bind GDP, they are 'off'. G proteins belong to the larger group of enzymes called GTPases. There are two classes of G proteins. The first function as monomeric small GTPases while the second form and function as heterotrimeric G protein complexes. The latter class of complexes are made up of alpha, beta and gamma subunits. In addition, the beta and gamma subunits can form a stable dimeric complex referred to as the beta-gamma complex. G proteins located within the cell are activated by G protein-coupled receptors that span the cell membrane. Signaling molecules bind to a domain of the GPCR located outside the cell. An intracellular GPCR domain in turn activates a G protein. The G protein activates a cascade of further signaling events that finally results in a change in cell function. G protein-coupled receptor and G proteins working together transmit signals from many hormones, neurotransmitters, and other signaling factors. G proteins regulate metabolic enzymes, ion channels, transporter, and other parts of the cell machinery, controlling transcription, motility, contractility, and secretion, which in turn regulate diverse systemic functions such as embryonic development, learning and memory, and homeostasis.

How to pronounce G protein?

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How to say G protein in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of G protein in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of G protein in Pythagorean Numerology is: 5

Examples of G protein in a Sentence

1. Gabrielle Francis:

   The protein helps to keep the blood sugar stable so it does n’t crash and wake you up -- and then there’s herbs like St. John's Wort, passionflower and Melissa Officinalis that all help to soothe the nervous system.

2. Kelly Pritchett:

   When glycogen is in short supply, your body also reverts to breaking down protein -- your muscles' building blocks -- for fuel.

3. Kaleigh McMordie:

   Frozen breakfast pastries consist of several forms of highly processed carbohydrates and sugar with no real nutritional value, not to mention all the chemical preservatives. Regular intake of these kinds of highly processed foods— high in refined white flour, refined sugar and high fructose corn syrup — is associated with a poor lipid profile, high triglyceride and LDL cholesterol levels in the blood, caused by high refined carb intake, is a major risk factor for heart disease. Skip the toaster pastries and opt for a breakfast that has a balance of healthy fat, protein, and carbohydrates from whole grains or fruit.

4. Angie Asche:

   If weight loss occurs after someone begins using a protein powder as a meal replacement, it would more likely be the result of an overall reduced calorie intake.

5. Robert Glatter:

   Consuming excess amounts of caffeine can lead to heart arrhythmias, elevated blood pressure and may actually increase your risk of dehydration. In the long run, choosing a low fat snack with fiber and protein is a healthier option than adding a scoop of protein to your coffee.

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/G_Protein
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/G_Protein
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=G protein