1. (noun)Columbia, Columbia River a North American river; rises in southwestern Canada and flows southward across Washington to form the border between Washington and Oregon before emptying into the Pacific; known for its salmon runs in the spring
2. (noun)Columbia a town in west central Tennessee
3. (noun)Columbia, capital of South Carolina capital and largest city in South Carolina; located in central South Carolina
4. (noun)Columbia a university town in central Missouri
5. (noun)Columbia University, Columbia a university in New York City