atherosclerosis, coronary artery disease(noun)
a stage of arteriosclerosis involving fatty deposits (atheromas) inside the arterial walls, thus narrowing the arteries
a form of arteriosclerosis characterized by irregular fatty deposits on the inner surface of large and medium-sized arteries; the deposits are associated with fibrosis and calcification of the inner layer of the arteries. Similar conditions may be found in swine and fowl. The deposits may become large enough to impede the blood circulation and in some cases may restrict the blood supply to the heart. Stedman
Origin: [Gr. + -logy.]
The clogging or hardening of arteries or blood vessels caused by plaques (accumulations of fatty deposits, usually cholesterol).
Atherosclerosis is a condition in which an artery wall thickens as a result of the accumulation of fatty materials such as cholesterol and triglyceride. It is a syndrome affecting arterial blood vessels, a chronic inflammatory response in the walls of arteries, caused largely by the accumulation of macrophage white blood cells and promoted by low-density lipoproteins without adequate removal of fats and cholesterol from the macrophages by functional high-density lipoproteins. It is commonly referred to as a hardening or furring of the arteries. It is caused by the formation of multiple plaques within the arteries. The atheromatous plaque is divided into three distinct components: ⁕The atheroma, which is the nodular accumulation of a soft, flaky, yellowish material at the center of large plaques, composed of macrophages nearest the lumen of the artery ⁕Underlying areas of cholesterol crystals ⁕Calcification at the outer base of older/more advanced lesions. The following terms are similar, yet distinct, in both spelling and meaning, and can be easily confused: arteriosclerosis, arteriolosclerosis, and atherosclerosis. Arteriosclerosis is a general term describing any hardening of medium or large arteries; arteriolosclerosis is any hardening of arterioles; atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. The term atherogenic is used for substances or processes that cause atherosclerosis.
U.S. National Library of Medicine
Thickening and loss of elasticity of the walls of medium and large muscular ARTERIES with lesions in the innermost layer of the artery (ARTERIAL INTIMA). This disease process of atherogenesis includes the retention of cholesterol-rich LIPOPROTEINS and their binding to PROTEOGLYCANS in the arterial intima, generation of proinflammatory molecules that recruit MACROPHAGES to the subendothelial space, formation of FOAM CELLS, and eventual calcification of the arterial wall. These arterial plaques (atheromas) contain CARBOHYDRATES; BLOOD; and CALCIUM.
The numerical value of Atherosclerosis in Chaldean Numerology is: 9
The numerical value of Atherosclerosis in Pythagorean Numerology is: 6
Sample Sentences & Example Usage
This is probably the largest study to date looking at the association of coffee consumption with a marker of subclinical atherosclerosis.
Typical post-stroke workup involves testing for many risk factors including carotid atherosclerosis, atrial fibrillation, hypercoagulable states, hypertension, high cholesterol, and diabetes among others, obstructive sleep apnea not only worsens all of these conditions but even with adjusting for other causes doubles the risk of stroke.
Images & Illustrations of Atherosclerosis
Translations for Atherosclerosis
From our Multilingual Translation Dictionary
Get even more translations for Atherosclerosis »
Find a translation for the Atherosclerosis definition in other languages:
Select another language:
Discuss these Atherosclerosis definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"Atherosclerosis." Definitions.net. STANDS4 LLC, 2017. Web. 27 May 2017. <http://www.definitions.net/definition/Atherosclerosis>.