Definitions for AMES TESTeɪmz

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Random House Webster's College Dictionary

Ames′ test`eɪmz(n.)

  1. a test that exposes a strain of bacteria to a chemical compound in order to determine the potential of the compound for causing cancer.

    Category: Medicine, Pharmacology

Origin of Ames test:

1975–80; after Bruce N. Ames (born 1928), U.S. biochemist, who developed the test

Freebase

  1. Ames test

    The Ames test is a biological assay to assess the mutagenic potential of chemical compounds. A positive test indicates that the chemical is mutagenic and therefore may act as a carcinogen, since cancer is often linked to mutation. However, a number of false-positives and false-negatives are known. The test serves as a quick and convenient assay to estimate the carcinogenic potential of a compound since standard carcinogen assays on rodents are time-consuming and expensive. The procedure is described in a series of papers from the early 1970s by Bruce Ames and his group at the University of California, Berkeley and work by Kristien Mortelmans at Stanford University.

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