Definitions for 3-alpha-hydroxysteroid dehydrogenase (b-specific)

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  1. 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)

    A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.


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