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 Definitions of 25-hydroxyvitamin d3 1-alpha-hydroxylase  

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Definition of '25-hydroxyvitamin d3 1-alpha-hydroxylase' U.S. National Library of Medicine 

1.  25-hydroxyvitamin d3 1-alpha-hydroxylase
A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP27B1 gene, converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol).

'25-hydroxyvitamin d3 1-alpha-hydroxylase' - Nearby Entries  

20-hydroxysteroid dehydrogenases  24,25-dihydroxyvitamin d 3  25-hydroxyvitamin d 2  25-hydroxyvitamin d3 1-alpha-hydroxylase  2h-benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-  2s albumins, plant  3' flanking region  



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